KMD Bioscience Ltd.

KMD Bioscience Ltd. is located in Wuqing District, northwest of Tianjin, China. The R&D center is located in Hongshan District, Wuhan City, Hubei Province. KMD Bioscience is a comprehensive innovative technology application enterprise integrating R&D, production and sales. The company aims to provide scientists with high-quality experimental outsourcing services (CRO services), including experimental design, routine genetic engineering experiments, recombinant protein expression and purification, recombinant antibody production, natural protein isolation and purification, virus isolation and other immunology related services. We would like to introduce our research platforms:

--- Phage Antibody Display Technology Platform

KMD Bioscience utilizes its own phage display (M13, T7 phage display technology platform) to provide customers with cost-effective recombinant Vhh antibody (Nanobody/Camel Nano Antibody) customization protocols, including animal immunization, library establishment, library screening, and in vitro expression of recombinant antibodies.

---Protein Expression and Purification Service Technology Platform

KMD Bioscience currently has four protein expression platforms that provide customers with comprehensive and superior protein expression technology services.

Mammalian Expression Platform: KMD Bioscience currently has cell-free CHO, Expi CHO, CHO-DG44, HEK293F, Vero and other cell lines for protein expression production. We use Gibco cell culture medium and related transfection reagents to ensure the high quality and high expression level of each batch of mammalian cell protein expression products. At the same time, KMD Bioscience has an expression vector system that is much higher than the commonly used protein expression vectors in the market, and can provide customers with high-purity protein.

Insect Cell Expression Platform: At present, the insect-expressing cells commonly used by KMD Bioscience are SF9, and the medium is Gibco in order to provide customers with high quality products. Using this protein expression platform, we have successfully prepared a variety of human transmembrane proteins, including a variety of GPCR family member proteins.

Prokaryotic Expression Platform: E. coli expression system has become very mature after years of development. However, an excellent expression strategy is essential if you want to obtain good soluble and high-yield protein expression in the E. coli expression system. KMD Bioscience's team of experts has massive experience and knowledge in protein expression and antibody production, and a very specific protocol will be provided to every customer.

Yeast Protein Expression Platform: Pichia pastoris, Saccharomyces cerevisiae and other protein expression systems, which are suitable for project requirements that require eukaryotic expression of protein, and it can make sure the yield and quality.

Plant Expression Platform: In order to provide better services, KMD Bioscience cooperates with domestic top research institutes to provide customers with plant protein expression services for transient transfection technology of genetic tobacco. The project requires only 4-6 weeks from design and construction to protein expression. The technology platform can provide customers with high-purity, high-quality plant-derived proteins in a short period of time, and has solved the problem that most plant proteins are insoluble or not expressed in the above-mentioned several protein expression systems.